a Record control number WOS:000298655800015

a ISSN 0340-6199

a Original cataloging agency NEU GrandLibrary

a Language code of text/sound track or separate title eng

a Classification number WS 18.2

b Item number .D47 2011

a Personal name Yalaz, Mehmet.

h Medium Electronic Document

a Title Desferrioxamine treatment of iron overload secondary to RH isoimmunization and intrauterine transfusion in a newborn infant

c Statement of responsibility, etc Mehmet Yalaz, Betul Siyah Bilgin, Ozge Altun Koroglu, Yilmaz Ay, Cigdem Arikan, Sermet Sagol, Mete Akisu, Nilgun Kultursay.

a Place of publication, distribution, etc Springer,

c Date of publication, distribution, etc 2011.

b Name of publisher, distributor, etc New York :

a Summary, etc Intrauterine transfusion is the standard of care in the management of severe Rh isoimmunization. Desferrioxamine has been used for the treatment of iron overload secondary to hemolysis and intrauterine transfusions in Rh isoimmunization cases. Here, we report a preterm infant born at 34 weeks of gestational age who had formerly received intrauterine transfusions for Rhesus hemolytic disease and presented with severe hyperferritinemia and elevated liver enzymes in the first week of life. Desferrioxamine treatment was started due to a ferritin level of 28,800 ng/ml and continued for 13 weeks. Although the treatment was successful, we observed resistant leukopenia which resolved after the cessation of treatment. In conclusion, iron overload secondary to intrauterine transfusions can be treated successfully with desferrioxamine; however, neonatologists must be aware of the possible side effects of this drug which has been used in only a limited number of newborns.

a Topical term or geographic name as entry element Cardiovascular system

a Topical term or geographic name as entry element Near East University Article

a Topical term or geographic name as entry element Yakın Doğu Üniversitesi Makale

a Topical term or geographic name as entry element Pediatrics

a Topical term or geographic name as entry element Newborn

a Topical term or geographic name as entry element Intrauterine transfusion

a Topical term or geographic name as entry element Rh isoimmunization

a Topical term or geographic name as entry element Desferrioxamine

a Topical term or geographic name as entry element Iron overload

g Relationship information NOV 2011, Vol 170 Issue 11, p1457-1460

x International Standard Serial Number 03406199

t Title European Journal Of Pedıatrıcs

u Uniform Resource Identifier http://library.neu.edu.tr:2048/login?url=http://dx.doi.org/10.1007/s00431-011-1521-7